I don't think there's much to discuss with persons who want to kill people or subject them to lengthy and harsh prison terms for wanting to enjoy some chemical pleasure in life...it would be like having a "discussion" with John Ashcroft or Pat Robertson.
As it happens, my personal drugs of choice are still (barely) legal; caffeine, alcohol, and nicotine. Marijuana simply puts me to sleep...and I don't need any help with that.
As far as we can tell, humans have sought intoxication in one form or another for
as far back as we can find evidence of human activity at all. Pots have been discovered with the remnents of beer and wine that are more than 7,000 years old!
All efforts at prohibition have completely failed; there is not a single instance in recorded history where prohibition actually worked...actually stopped the use of the prohibited substance. Temporarily reduced, yes; stopped, no.
The human cost of prohibition is immeasurable...the shattered lives and unnecessary deaths, the pain and suffering, etc., the creation of gestapo-like drug police and swollen gulags and corruption from top to bottom, etc. This is both the legacy and the current practice of chemical neo-puritanism.
It's really something to be proud of, isn't it?