[Igor Antunov]

Background
Several disorders might require vaginal reconstruction, such as congenital abnormalities, injury, or cancer. Reconstructive techniques for which non-vaginal tissue is used can be associated with complications. We assessed the use of engineered vaginal organs in four patients with vaginal aplasia caused by Mayer-Rokitansky-Küster-Hauser syndrome (MRKHS).
Methods
We invited to participate four consecutive patients who presented over a 3-year period with congenital vaginal aplasia due to MRKHS. Patients were aged 13—18 years. We obtained a vulvar biopsy of autologous tissue from every patient. We cultured, expanded, and seeded epithelial and muscle cells onto biodegradable scaffolds. The organs were constructed and allowed to mature in an incubator in a facility approved for human-tissue manufacturing. We used a perineal approach to surgically implant these organs. We recorded history, physical examination, vaginoscopy, serial tissue biopsies, MRIs, and self-administered Female Sexual Function Index questionnaire results for all patients, with a follow-up of up to 8 years.
Findings
We noted no long-term postoperative surgical complications. Yearly serial biopsies showed a tri-layered structure, consisting of an epithelial cell-lined lumen surrounded by matrix and muscle, with expected components of vaginal tissue present. Immunohistochemical analysis confirmed the presence of phenotypically normal smooth muscle and epithelia. The MRIs, which showed the extent of the vaginal aplasia before surgery, showed the engineered organs and the absence of abnormalities after surgery, which was confirmed with yearly vaginoscopy. A validated self-administered Female Sexual Function Index questionnaire showed variables in the normal range in all areas tested, such as desire, arousal, lubrication, orgasm, satisfaction, and painless intercourse.
Interpretation
Vaginal organs, engineered from the patient's own cells and implanted, showed normal structural and functional variables with a follow-up of up to 8 years. These technologies could be useful in patients requiring vaginal reconstruction.

http://www.thelancet.com/journals/lance ... 0/abstract

Many uses, I'm sure.

[Thompson_NCL]

That's an ominous comment, Igor.

[benpenguin]

I pretty sure the lady boys and transexuals will be elated by this news.

[OnTPath]

That invention could lead to some really hype Art in being performance.

Imagine Femen members, covered all over with implanted vaginas filled with chickens.

Can I implant them in my garden soon ? You know they would nicely complement my Orchids.

[teedoffshrew]

American Dad will finally get his wish; to equip every soldier with a vagina. Let's hope these falsies are as resilient as a natural vagina. There is no substitute for quality

[nucklepunche]

I'm guessing plenty of men will like to get them implanted in the palm of their hands.

[benpenguin]

Will their hands get pregnant from this? If then...should his son/daughter call him father/mother?

[Varax]

Yet another step forward for laboratory grown organs that will help with many medical problems. Great for transsexuals too.

[Igor Antunov]

I'm guessing plenty of men will like to get them implanted in the palm of their hands.

The imagery this invokes makes me sick for some reason.