FiveofSwords wrote:Thanks for confirming that you don't get it
Tajima's D reflects the expansion or contraction of population size, the strength of selection, and population structure. It is usually used to test whether the population follows three assumptions: (i) constant population size over time, (ii) neutral evolution, and (iii) no population structure.
*
Fumio Tajima, Statistical method for testing the neutral mutation hypothesis by DNA polymorphism. Genetics, 123 (1989), pp. 585-595I will still try to explain it like you are 5
1. A high number usually means selection has strengthened and the population has fallen due to environmental changes or disease.
2(a) A low number means selection has weakened and the population has risen after a random mutation has been selected that mitigates the effects of changes in the environment or disease.
It should quickly revert to 3
2(b) Of course, it could also mean that because the population was so low after mitigation they started fucking their neighbours.
They should become one population and revert to 3.
3. A middling number shows everything is hunky-dory.
"All issues are political issues, and politics itself is a mass of lies, evasions, folly, hatred and schizophrenia" Orwell
E l/r -10 : L/A -7.64